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Counties with highest COVID-19 infection rates in Alabama

The vaccine deployment in December 2020 signaled a turning point in the COVID-19 pandemic. By the end of May 2021, 40% of the U.S. population was fully vaccinated. But as vaccination rates lagged over the summer, new surges of COVID-19 came, including Delta in the summer of 2021, and now the Omicron variant, which comprises the majority of cases in the U.S.

Researchers around the world have reported that Omicron is more transmissible than Delta, making breakthrough and repeat infections more likely.

The United States as of May 18 reached over 1 million COVID-19-related deaths and 83.4 million COVID-19 cases, according to Johns Hopkins University. Currently, 66.5% of the population is fully vaccinated, and 46.4% of vaccinated people have received booster doses.

Stacker compiled a list of the counties with highest COVID-19 infection rates in Alabama using data from the U.S. Department of Health & Human Services and vaccination data from Covid Act Now. Counties are ranked by the highest infection rate per 100,000 residents within the week leading up to May 17, 2022. Cumulative cases per 100,000 served as a tiebreaker.

Keep reading to see whether your county ranks among the highest COVID-19 infection rates in your state.

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#50. Fayette County, AL

– New cases per 100k in the past week: 25 (4 new cases, 0% change from previous week)
– Cumulative cases per 100k: 30,591 (4,987 total cases)
— 14.8% more cases per 100k residents than Alabama
– Cumulative deaths per 100k: 589 (96 total deaths)
— 47.3% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 35.1% (5,718 fully vaccinated)

DXR // Wikimedia Commons

#49. Dallas County, AL

– New cases per 100k in the past week: 27 (10 new cases, +100% change from previous week)
– Cumulative cases per 100k: 22,674 (8,434 total cases)
— 14.9% less cases per 100k residents than Alabama
– Cumulative deaths per 100k: 656 (244 total deaths)
— 64.0% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 45.7% (16,998 fully vaccinated)

Wmr36104 // Wikimedia Commons

#48. Geneva County, AL

– New cases per 100k in the past week: 27 (7 new cases, -36% change from previous week)
– Cumulative cases per 100k: 24,723 (6,495 total cases)
— 7.2% less cases per 100k residents than Alabama
– Cumulative deaths per 100k: 624 (164 total deaths)
— 56.0% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 40.4% (10,620 fully vaccinated)

Rivers A. Langley; SaveRivers // Wikimedia Commons

#47. Elmore County, AL

– New cases per 100k in the past week: 28 (23 new cases, -15% change from previous week)
– Cumulative cases per 100k: 28,847 (23,426 total cases)
— 8.3% more cases per 100k residents than Alabama
– Cumulative deaths per 100k: 427 (347 total deaths)
— 6.8% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 46.7% (37,886 fully vaccinated)

Rivers Langley; SaveRivers // Wikimedia Commons

#46. Crenshaw County, AL

– New cases per 100k in the past week: 29 (4 new cases, +300% change from previous week)
– Cumulative cases per 100k: 27,846 (3,835 total cases)
— 4.5% more cases per 100k residents than Alabama
– Cumulative deaths per 100k: 726 (100 total deaths)
— 81.5% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 34.6% (4,759 fully vaccinated)

Dailynetworks // Wikimedia Commons

#45. Colbert County, AL

– New cases per 100k in the past week: 29 (16 new cases, +14% change from previous week)
– Cumulative cases per 100k: 29,625 (16,365 total cases)
— 11.2% more cases per 100k residents than Alabama
– Cumulative deaths per 100k: 474 (262 total deaths)
— 18.5% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 48.2% (26,629 fully vaccinated)

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#44. Lawrence County, AL

– New cases per 100k in the past week: 30 (10 new cases, +43% change from previous week)
– Cumulative cases per 100k: 23,354 (7,689 total cases)
— 12.3% less cases per 100k residents than Alabama
– Cumulative deaths per 100k: 486 (160 total deaths)
— 21.5% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 47.3% (15,564 fully vaccinated)

Altairisfar // Wikicommons

#43. Mobile County, AL

– New cases per 100k in the past week: 30 (124 new cases, +28% change from previous week)
– Cumulative cases per 100k: 27,432 (113,351 total cases)
— 3.0% more cases per 100k residents than Alabama
– Cumulative deaths per 100k: 400 (1,653 total deaths)
— 0.0% less deaths per 100k residents than Alabama
– Population that is fully vaccinated: 50.2% (207,229 fully vaccinated)

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#42. Walker County, AL

– New cases per 100k in the past week: 30 (19 new cases, +58% change from previous week)
– Cumulative cases per 100k: 29,546 (18,768 total cases)
— 10.9% more cases per 100k residents than Alabama
– Cumulative deaths per 100k: 704 (447 total deaths)
— 76.0% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 47.4% (30,124 fully vaccinated)

Wayne James // Shutterstock

#41. Lauderdale County, AL

– New cases per 100k in the past week: 32 (30 new cases, -9% change from previous week)
– Cumulative cases per 100k: 26,102 (24,204 total cases)
— 2.0% less cases per 100k residents than Alabama
– Cumulative deaths per 100k: 428 (397 total deaths)
— 7.0% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 46.8% (43,441 fully vaccinated)

Rudi Weikard // Wikimedia Commons

#40. Franklin County, AL

– New cases per 100k in the past week: 32 (10 new cases, 0% change from previous week)
– Cumulative cases per 100k: 31,592 (9,908 total cases)
— 18.6% more cases per 100k residents than Alabama
– Cumulative deaths per 100k: 443 (139 total deaths)
— 10.8% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 43.9% (13,776 fully vaccinated)

Kreeder13 // Wikimedia Commons

#39. Pike County, AL

– New cases per 100k in the past week: 33 (11 new cases, +1,000% change from previous week)
– Cumulative cases per 100k: 22,924 (7,591 total cases)
— 13.9% less cases per 100k residents than Alabama
– Cumulative deaths per 100k: 405 (134 total deaths)
— 1.3% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 42.4% (14,032 fully vaccinated)

Rivers Langley; SaveRivers // Wikimedia Commons

#38. Calhoun County, AL

– New cases per 100k in the past week: 33 (37 new cases, +61% change from previous week)
– Cumulative cases per 100k: 28,580 (32,468 total cases)
— 7.3% more cases per 100k residents than Alabama
– Cumulative deaths per 100k: 552 (627 total deaths)
— 38.0% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 47.1% (53,555 fully vaccinated)

Altairisfar // Wikimedia Commons

#37. Clarke County, AL

– New cases per 100k in the past week: 34 (8 new cases, +100% change from previous week)
– Cumulative cases per 100k: 30,290 (7,155 total cases)
— 13.7% more cases per 100k residents than Alabama
– Cumulative deaths per 100k: 428 (101 total deaths)
— 7.0% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 51.3% (12,116 fully vaccinated)

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#36. DeKalb County, AL

– New cases per 100k in the past week: 38 (27 new cases, +80% change from previous week)
– Cumulative cases per 100k: 26,295 (18,804 total cases)
— 1.3% less cases per 100k residents than Alabama
– Cumulative deaths per 100k: 461 (330 total deaths)
— 15.3% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 34.1% (24,388 fully vaccinated)

Chris Pruitt // Wikimedia Commons

#35. Cullman County, AL

– New cases per 100k in the past week: 38 (32 new cases, +14% change from previous week)
– Cumulative cases per 100k: 29,437 (24,659 total cases)
— 10.5% more cases per 100k residents than Alabama
– Cumulative deaths per 100k: 438 (367 total deaths)
— 9.5% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 38.3% (32,105 fully vaccinated)

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#34. Wilcox County, AL

– New cases per 100k in the past week: 39 (4 new cases, +300% change from previous week)
– Cumulative cases per 100k: 27,890 (2,893 total cases)
— 4.7% more cases per 100k residents than Alabama
– Cumulative deaths per 100k: 443 (46 total deaths)
— 10.8% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 54.0% (5,603 fully vaccinated)

Rivers Langley; SaveRivers // Wikimedia Commons

#33. Cleburne County, AL

– New cases per 100k in the past week: 40 (6 new cases, 0% change from previous week)
– Cumulative cases per 100k: 23,917 (3,566 total cases)
— 10.2% less cases per 100k residents than Alabama
– Cumulative deaths per 100k: 463 (69 total deaths)
— 15.8% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 28.9% (4,311 fully vaccinated)

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#32. Pickens County, AL

– New cases per 100k in the past week: 40 (8 new cases, +100% change from previous week)
– Cumulative cases per 100k: 26,458 (5,273 total cases)
— 0.7% less cases per 100k residents than Alabama
– Cumulative deaths per 100k: 512 (102 total deaths)
— 28.0% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 49.9% (9,945 fully vaccinated)

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#31. Marshall County, AL

– New cases per 100k in the past week: 40 (39 new cases, +56% change from previous week)
– Cumulative cases per 100k: 28,359 (27,444 total cases)
— 6.5% more cases per 100k residents than Alabama
– Cumulative deaths per 100k: 407 (394 total deaths)
— 1.8% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 45.9% (44,402 fully vaccinated)

Chris Pruitt // Wikimedia Commons

#30. Autauga County, AL

– New cases per 100k in the past week: 43 (24 new cases, +85% change from previous week)
– Cumulative cases per 100k: 28,406 (15,870 total cases)
— 6.6% more cases per 100k residents than Alabama
– Cumulative deaths per 100k: 387 (216 total deaths)
— 3.3% less deaths per 100k residents than Alabama
– Population that is fully vaccinated: 44.4% (24,807 fully vaccinated)

Rudi Weikard // Wikimedia Commons

#29. Blount County, AL

– New cases per 100k in the past week: 47 (27 new cases, +238% change from previous week)
– Cumulative cases per 100k: 25,966 (15,015 total cases)
— 2.5% less cases per 100k residents than Alabama
– Cumulative deaths per 100k: 420 (243 total deaths)
— 5.0% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 31.8% (18,400 fully vaccinated)

Rivers A. Langley; SaveRivers // Wikimedia Commons

#28. Tallapoosa County, AL

– New cases per 100k in the past week: 47 (19 new cases, +90% change from previous week)
– Cumulative cases per 100k: 28,370 (11,452 total cases)
— 6.5% more cases per 100k residents than Alabama
– Cumulative deaths per 100k: 580 (234 total deaths)
— 45.0% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 38.7% (15,632 fully vaccinated)

MPearsallArt // Wikimedia Commons

#27. Morgan County, AL

– New cases per 100k in the past week: 47 (56 new cases, +44% change from previous week)
– Cumulative cases per 100k: 30,236 (36,186 total cases)
— 13.5% more cases per 100k residents than Alabama
– Cumulative deaths per 100k: 433 (518 total deaths)
— 8.3% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 43.8% (52,389 fully vaccinated)

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#26. Sumter County, AL

– New cases per 100k in the past week: 48 (6 new cases, +100% change from previous week)
– Cumulative cases per 100k: 20,882 (2,595 total cases)
— 21.6% less cases per 100k residents than Alabama
– Cumulative deaths per 100k: 410 (51 total deaths)
— 2.5% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 51.7% (6,428 fully vaccinated)

Rivers Langley; SaveRivers // Wikimedia Commons

#25. Chambers County, AL

– New cases per 100k in the past week: 48 (16 new cases, +100% change from previous week)
– Cumulative cases per 100k: 25,594 (8,511 total cases)
— 3.9% less cases per 100k residents than Alabama
– Cumulative deaths per 100k: 487 (162 total deaths)
— 21.8% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 31.6% (10,503 fully vaccinated)

Calvin Beale // Wikimedia Commons

#24. Coffee County, AL

– New cases per 100k in the past week: 52 (27 new cases, +8% change from previous week)
– Cumulative cases per 100k: 26,088 (13,655 total cases)
— 2.1% less cases per 100k residents than Alabama
– Cumulative deaths per 100k: 441 (231 total deaths)
— 10.3% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 47.5% (24,874 fully vaccinated)

Rivers Langley; SaveRivers // Wikimedia Commons

#23. Henry County, AL

– New cases per 100k in the past week: 52 (9 new cases, +80% change from previous week)
– Cumulative cases per 100k: 26,655 (4,586 total cases)
— 0.1% more cases per 100k residents than Alabama
– Cumulative deaths per 100k: 442 (76 total deaths)
— 10.5% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 45.6% (7,845 fully vaccinated)

Rivers Langley; SaveRivers // Wikimedia Commons

#22. Barbour County, AL

– New cases per 100k in the past week: 53 (13 new cases, +160% change from previous week)
– Cumulative cases per 100k: 23,041 (5,688 total cases)
— 13.5% less cases per 100k residents than Alabama
– Cumulative deaths per 100k: 397 (98 total deaths)
— 0.8% less deaths per 100k residents than Alabama
– Population that is fully vaccinated: 45.6% (11,248 fully vaccinated)

Library of Congress

#21. Lee County, AL

– New cases per 100k in the past week: 56 (92 new cases, +70% change from previous week)
– Cumulative cases per 100k: 23,047 (37,922 total cases)
— 13.5% less cases per 100k residents than Alabama
– Cumulative deaths per 100k: 207 (341 total deaths)
— 48.3% less deaths per 100k residents than Alabama
– Population that is fully vaccinated: 40.4% (66,471 fully vaccinated)

Carol M. Highsmith/Library of Congress // Wikimedia Commons

#20. Houston County, AL

– New cases per 100k in the past week: 56 (59 new cases, +7% change from previous week)
– Cumulative cases per 100k: 24,387 (25,821 total cases)
— 8.5% less cases per 100k residents than Alabama
– Cumulative deaths per 100k: 478 (506 total deaths)
— 19.5% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 43.4% (45,984 fully vaccinated)

Rivers A. Langley; SaveRivers // Wikimedia Commons

#19. Coosa County, AL

– New cases per 100k in the past week: 56 (6 new cases, +100% change from previous week)
– Cumulative cases per 100k: 27,919 (2,977 total cases)
— 4.8% more cases per 100k residents than Alabama
– Cumulative deaths per 100k: 544 (58 total deaths)
— 36.0% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 40.8% (4,347 fully vaccinated)

Rivers Langley; SaveRivers // Wikimedia Commons

#18. Talladega County, AL

– New cases per 100k in the past week: 56 (45 new cases, +105% change from previous week)
– Cumulative cases per 100k: 28,023 (22,412 total cases)
— 5.2% more cases per 100k residents than Alabama
– Cumulative deaths per 100k: 471 (377 total deaths)
— 17.8% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 36.7% (29,360 fully vaccinated)

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#17. Escambia County, AL

– New cases per 100k in the past week: 57 (21 new cases, -50% change from previous week)
– Cumulative cases per 100k: 27,533 (10,086 total cases)
— 3.4% more cases per 100k residents than Alabama
– Cumulative deaths per 100k: 467 (171 total deaths)
— 16.8% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 36.7% (13,445 fully vaccinated)

Tracy Burroughs Brown // Shutterstock

#16. Tuscaloosa County, AL

– New cases per 100k in the past week: 59 (123 new cases, +66% change from previous week)
– Cumulative cases per 100k: 26,910 (56,337 total cases)
— 1.0% more cases per 100k residents than Alabama
– Cumulative deaths per 100k: 375 (786 total deaths)
— 6.3% less deaths per 100k residents than Alabama
– Population that is fully vaccinated: 43.9% (91,917 fully vaccinated)

Michael Rivera // Wikimedia Commons

#15. Dale County, AL

– New cases per 100k in the past week: 61 (30 new cases, +88% change from previous week)
– Cumulative cases per 100k: 26,342 (12,953 total cases)
— 1.1% less cases per 100k residents than Alabama
– Cumulative deaths per 100k: 470 (231 total deaths)
— 17.5% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 48.2% (23,687 fully vaccinated)

Rudi Weikard // Wikimedia Commons

#14. St. Clair County, AL

– New cases per 100k in the past week: 61 (55 new cases, +10% change from previous week)
– Cumulative cases per 100k: 28,400 (25,421 total cases)
— 6.6% more cases per 100k residents than Alabama
– Cumulative deaths per 100k: 465 (416 total deaths)
— 16.3% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 39.3% (35,186 fully vaccinated)

Altairisfar // Wikimedia Commons

#13. Lowndes County, AL

– New cases per 100k in the past week: 62 (6 new cases, -25% change from previous week)
– Cumulative cases per 100k: 27,051 (2,631 total cases)
— 1.6% more cases per 100k residents than Alabama
– Cumulative deaths per 100k: 792 (77 total deaths)
— 98.0% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 51.3% (4,986 fully vaccinated)

Rudi Weikard // Wikimedia Commons

#12. Marion County, AL

– New cases per 100k in the past week: 64 (19 new cases, +217% change from previous week)
– Cumulative cases per 100k: 27,460 (8,158 total cases)
— 3.1% more cases per 100k residents than Alabama
– Cumulative deaths per 100k: 512 (152 total deaths)
— 28.0% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 36.7% (10,893 fully vaccinated)

Chris Pruitt // wikicommons

#11. Montgomery County, AL

– New cases per 100k in the past week: 68 (154 new cases, +73% change from previous week)
– Cumulative cases per 100k: 24,442 (55,357 total cases)
— 8.2% less cases per 100k residents than Alabama
– Cumulative deaths per 100k: 419 (948 total deaths)
— 4.8% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 52.5% (118,959 fully vaccinated)

JNix // Shutterstock

#10. Clay County, AL

– New cases per 100k in the past week: 68 (9 new cases, +200% change from previous week)
– Cumulative cases per 100k: 30,978 (4,100 total cases)
— 16.3% more cases per 100k residents than Alabama
– Cumulative deaths per 100k: 620 (82 total deaths)
— 55.0% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 41.9% (5,549 fully vaccinated)

Jodybwiki // Wikimedia Commons

#9. Baldwin County, AL

– New cases per 100k in the past week: 69 (155 new cases, +60% change from previous week)
– Cumulative cases per 100k: 25,048 (55,916 total cases)
— 6.0% less cases per 100k residents than Alabama
– Cumulative deaths per 100k: 305 (681 total deaths)
— 23.8% less deaths per 100k residents than Alabama
– Population that is fully vaccinated: 51.2% (114,205 fully vaccinated)

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#8. Bibb County, AL

– New cases per 100k in the past week: 71 (16 new cases, +220% change from previous week)
– Cumulative cases per 100k: 28,860 (6,463 total cases)
— 8.3% more cases per 100k residents than Alabama
– Cumulative deaths per 100k: 469 (105 total deaths)
— 17.3% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 34.8% (7,802 fully vaccinated)

Mccallk69 // Shutterstock

#7. Macon County, AL

– New cases per 100k in the past week: 72 (13 new cases, +550% change from previous week)
– Cumulative cases per 100k: 21,513 (3,887 total cases)
— 19.2% less cases per 100k residents than Alabama
– Cumulative deaths per 100k: 470 (85 total deaths)
— 17.5% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 48.3% (8,734 fully vaccinated)

Carol M. Highsmith // Wikimedia Commons

#6. Limestone County, AL

– New cases per 100k in the past week: 78 (77 new cases, +126% change from previous week)
– Cumulative cases per 100k: 25,369 (25,094 total cases)
— 4.8% less cases per 100k residents than Alabama
– Cumulative deaths per 100k: 297 (294 total deaths)
— 25.8% less deaths per 100k residents than Alabama
– Population that is fully vaccinated: 39.1% (38,710 fully vaccinated)

Myself – Nathon Morris // Wikimedia Commons

#5. Lamar County, AL

– New cases per 100k in the past week: 80 (11 new cases, +450% change from previous week)
– Cumulative cases per 100k: 27,135 (3,746 total cases)
— 1.9% more cases per 100k residents than Alabama
– Cumulative deaths per 100k: 471 (65 total deaths)
— 17.8% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 44.2% (6,096 fully vaccinated)

Carol M. Highsmith // Wikimedia Commons

#4. Hale County, AL

– New cases per 100k in the past week: 82 (12 new cases, +500% change from previous week)
– Cumulative cases per 100k: 32,387 (4,745 total cases)
— 21.6% more cases per 100k residents than Alabama
– Cumulative deaths per 100k: 724 (106 total deaths)
— 81.0% more deaths per 100k residents than Alabama
– Population that is fully vaccinated: 61.6% (9,019 fully vaccinated)

M Floyd // Flickr

#3. Jefferson County, AL

– New cases per 100k in the past week: 83 (545 new cases, +61% change from previous week)
– Cumulative cases per 100k: 28,264 (186,139 total cases)
— 6.1% more cases per 100k residents than Alabama
– Cumulative deaths per 100k: 360 (2,373 total deaths)
— 10.0% less deaths per 100k residents than Alabama
– Population that is fully vaccinated: 58.5% (385,388 fully vaccinated)

Rivers Langley; SaveRivers // Wikimedia Commons

#2. Shelby County, AL

– New cases per 100k in the past week: 91 (198 new cases, +72% change from previous week)
– Cumulative cases per 100k: 28,180 (61,348 total cases)
— 5.8% more cases per 100k residents than Alabama
– Cumulative deaths per 100k: 208 (452 total deaths)
— 48.0% less deaths per 100k residents than Alabama
– Population that is fully vaccinated: 36.4% (79,276 fully vaccinated)

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#1. Madison County, AL

– New cases per 100k in the past week: 101 (378 new cases, +44% change from previous week)
– Cumulative cases per 100k: 24,280 (90,544 total cases)
— 8.9% less cases per 100k residents than Alabama
– Cumulative deaths per 100k: 260 (968 total deaths)
— 35.0% less deaths per 100k residents than Alabama
– Population that is fully vaccinated: 62.5% (233,073 fully vaccinated)